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TAK1 Negatively Regulates NF-κB and p38 MAP Kinase Activation in Gr-1+CD11b+ Neutrophils

✍ Scribed by Adebusola Alagbala Ajibade; Qinfu Wang; Jun Cui; Jia Zou; Xiaojun Xia; Mingjun Wang; Yanzheng Tong; Wei Hui; Dou Liu; Bing Su; Helen Y. Wang; Rong-Fu Wang


Book ID
116570963
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
35 KB
Volume
36
Category
Article
ISSN
1074-7613

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## Abstract G‐protein‐coupled receptor kinase 2 (GRK2) is a member of a kinase family originally discovered for its role in the phosphorylation and desensitization of G‐protein‐coupled receptors. It is expressed in high levels in myeloid cells and its levels are altered in many inflammatory disorde