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Tailoring Polymeric Hydrogels through Cyclodextrin Host–Guest Complexation

✍ Scribed by Xuhong Guo; Jie Wang; Li Li; Duc-Truc Pham; Philip Clements; Stephen F. Lincoln; Bruce L. May; Qingchuan Chen; Li Zheng; Robert K. Prud'homme

Book ID
102493683
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
485 KB
Volume
31
Category
Article
ISSN
1022-1336

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✦ Synopsis

Abstract

A close correllation between molecular‐level interactions and macroscopic characteristics of polymer networks exists. The characteristics of the polymeric hydrogels assembled from β‐cyclodextrin (β‐CD) and adamantyl (AD) substituted poly(acrylate)s can be tailored through selective host–guest complexation between β‐CD and AD substituents and their tethers. Dominantly, steric effects and competitive intra‐ and intermolecular host–guest complexation are found to control poly(acrylate) isomeric inter‐strand linkage in polymer network formation. This understanding of the factors involved in polymeric hydrogel formation points the way towards the construction of increasingly sophisticated biocompatible materials.

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