Tailor-Made Fructooligosaccharides by a Combination of Substrate and Genetic Engineering
✍ Scribed by Alga Zuccaro; Sven Götze; Susanne Kneip; Petra Dersch; Jürgen Seibel
- Book ID
- 101823189
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 455 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1439-4227
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The combination of sucrose analogues as novel substrates (substrate engineering) and highly active recombinant β‐fructofuranosidase from A. niger (genetic engineering) provides a new powerful tool for the efficient preparative synthesis of tailor‐made saccharides of the important 1‐kestose and 1‐nystose type headed with different monosaccharides of interest. These novel compounds have been isolated. They did not display toxic effects or suppress cell growth in initial studies, making these new compounds potential candidates for prebiotics.
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