𝔖 Bobbio Scriptorium
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Tailor-Made Fructooligosaccharides by a Combination of Substrate and Genetic Engineering

✍ Scribed by Alga Zuccaro; Sven Götze; Susanne Kneip; Petra Dersch; Jürgen Seibel


Book ID
101823189
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
455 KB
Volume
9
Category
Article
ISSN
1439-4227

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✦ Synopsis


Abstract

The combination of sucrose analogues as novel substrates (substrate engineering) and highly active recombinant β‐fructofuranosidase from A. niger (genetic engineering) provides a new powerful tool for the efficient preparative synthesis of tailor‐made saccharides of the important 1‐kestose and 1‐nystose type headed with different monosaccharides of interest. These novel compounds have been isolated. They did not display toxic effects or suppress cell growth in initial studies, making these new compounds potential candidates for prebiotics.


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