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Tafluprost protects rat retinal ganglion cells from apoptosis in vitro and in vivo

โœ Scribed by Akiyasu Kanamori; Maiko Naka; Masahide Fukuda; Makoto Nakamura; Akira Negi

Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
302 KB
Volume
247
Category
Article
ISSN
0065-6100

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Adenoviral-mediated transfer of ciliary neurotrophic factor (CNTF) to the retina rescued retinal ganglion cells (RGCs) from axotomy-induced apoptosis, presumably via activation of the high affinity CNTF receptor alpha (CNTFRalpha) expressed on RGCs. CNTF can also activate astrocytes, via its low aff