Tacrolimus and cyclosporine efficacy in high-risk kidney transplantation
โ Scribed by I. A. Hauser, H.-N. Neumayer
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 216 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0934-0874
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๐ SIMILAR VOLUMES
The pharmacokinetic parameters of cyclosporine (CsA) were determined in 23 kidney transplant recipients and 19 children with nephrotic syndrome, after intravenous and oral administration. The mean bioavailability was 39 %, blood clearance was 0.55 1 โข h -1 โข kg -1 and volume of distribution at stea
The development of atherosclerotic cardiovascular complications is a common and serious problem for the long-term survivors of organ transplantation. Cyclosporine A plus steroid-based immuno-suppression regimens in these patients are associated with the development of hypertension, hyperlipidemia, o