Tackling overtreatment of prostate cancer : The role of comorbidity
โ Scribed by Jennifer Beebe-Dimmer; Vahakn Shahinian
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 74 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
Despite calls for more conservative management of localized prostate cancer in both the published literature and in practice guidelines, overtreatment remains rampant. The troubling implication is that, unless prediction tools are virtually perfect in their ability to discern which men will or will not die from their prostate cancer, patients may continue to choose aggressive interventions.
๐ SIMILAR VOLUMES
An understanding of the natural history of changes in prostate-specific antigen (PSA) may be valuable as a surrogate view of prostate dynamics, as a method to differentiate between benign and malignant growth, and as a means to assess the use of PSA as a tool for monitoring activity of chemopreventi
The polyamines are normal cell constituents considered to have an important role in the regulation of proliferation and differentiation. DFMO is an irreversible, enzyme-activated, suicide inhibitor of ornithine decarboxylase (ODC), the enzyme responsible forthe first and rate-limiting step in mammal