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Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergic airway disease

✍ Scribed by Claude Bertrand; Pierangelo Geppetti


Book ID
116103764
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
390 KB
Volume
17
Category
Article
ISSN
0165-6147

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SUMMARY: Tachykinins are potent bronchoconstrictors. Here we have used novel highly selective agonists and antagonists to characterize tachykinin receptors mediating bronchoconstriction and hypotension in anaesthetized, paralysed guinea-pigs. Total lung resistance \(\left(R_{L}\right)\) and dynamic