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TACE is required for fetal murine cardiac development and modeling

โœ Scribed by Wei Shi; Hui Chen; Jianping Sun; Sue Buckley; Jingsong Zhao; Kathryn D Anderson; Roberta G Williams; David Warburton


Book ID
117093048
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
448 KB
Volume
261
Category
Article
ISSN
0012-1606

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## Abstract We hypothesized that PDGFโ€B/PDGFRโ€ฮฒโ€signaling is important in the cardiac contribution of epicardiumโ€derived cells and cardiac neural crest, cell lineages crucial for heart development. We analyzed hearts of different embryonic stages of both __Pdgfโ€bโˆ’/โˆ’__ and __Pdgfrโ€ฮฒโˆ’/โˆ’__ mouse embry