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TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton

✍ Scribed by Ryoji Yao; Yasuko Natsume; Tetsuo Noda


Book ID
108583847
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
311 KB
Volume
98
Category
Article
ISSN
1347-9032

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PRS3 is one of a family of five genes encoding phosphoribosylpyrophosphate synthetase, an enzyme which catalyses the first step in a variety of biosynthetic pathways, including purine and pyrimidine biosynthesis. We report here that prs3Delta mutants have a number of phenotypes that suggest an unexp