A case study on the in silico absorption
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Ivana Kocic; Irena Homsek; Mirjana Dacevic; Sandra Grbic; Jelena Parojcic; Katar
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Article
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2012
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John Wiley and Sons
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English
β 388 KB
π 2 views
## ABSTRACT The aim of this case study was to develop a drugβspecific absorption model for levothyroxine (LT4) using mechanistic gastrointestinal simulation technology (GIST) implemented in the GastroPlusβ’ software package. The required input parameters were determined experimentally, __in silico__