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T3P (propylphosphonic anhydride) mediated conversion of Nα-protected amino/peptide acids into thioacids

✍ Scribed by Chilakapati Madhu; Basavaprabhu; T.M. Vishwanatha; Vommina V. Sureshbabu


Book ID
113930501
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
480 KB
Volume
53
Category
Article
ISSN
0040-4039

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Two new glycosyl amino acids N'~-Fmoc-Ser[Ac4-fl-D-Galp-(1 ~ 3)-Ac2-a-D-GalN3P]-OPf p and N'~-Fmoc-Thr[Ac4-/3-D-Galp-(1 ~ 3)-Ac2-a-D-GalN3p]-OPf p were synthesized. Glycosylation of N'~-Fmoc-Ser-OPf p or N ~-Fmoc-Thr-OPfp with protected/3-o-Gal-( 1 -~ 3)-D-GaIN 3 donors afforded the glycosyl amino a