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t(3;12)(q26;q14) in polycythemia vera is associated with upregulation of the HMGA2 gene

✍ Scribed by Storlazzi, C T; Albano, F; Locunsolo, C; Lonoce, A; Funes, S; Guastadisegni, M C; Cimarosto, L; Impera, L; D'Addabbo, P; Panagopoulos, I

Book ID
110056934
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
189 KB
Volume
20
Category
Article
ISSN
0887-6924

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The EVll DNA-binding protein gene on chromosome 3q26 has been reported to be activated in some leukemia cells with alterations in 3q26. We present an acute myelogenous leukemia (AML) patient with a rare chromosomal translocation, t(3;13)(q26.2;q13-14). By reverse transcription-polymerase chain react