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T1values of phosphomonoester and phosphocreatine of brain show no significant change during development

✍ Scribed by Kazutoshi Hida; Ingrid L. Kwee; Tsutomu Nakada

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 224 KB
Volume: 27
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910270117

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Changes in apparent ^31^P spin‐lattice relaxation times (T~1~) associated with brain development were investigated in rat pups. While analysis of variance showed strong age dependency in [PME]/[ATP] and [PCr]/[ATP], the T~1~ values of PME, PCr, and ATP did not show any age dependency. The studies indicate that in contrast to the data which indicated aging‐related changes in the T^1^ values of PME, the observed changes in PME during neonatal development are likely to be quantitative in nature.

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