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T1955 Retrospective Comparison of Oral vs. Intravenous Proton-Pump Inhibitor Therapy in Patients with Acute Peptic Ulcer Bleeding and High-Risk Endoscopic Stigmata

✍ Scribed by Henry, Michael J.; Puchakayala, Bharat K.; Raghavendra, Meghana; Mathiason, Michelle A.

Book ID: 122733534
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 70 KB
Volume: 136
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(09)62802-X

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## Abstract ## Background Rebleeding from peptic ulcers is a major contributor to death. This study compared standard (40-mg intravenous infusion of omeprazole once daily for 3 days) and high-dose (80-mg bolus of omeprazole followed by 8-mg/h infusion for 72 h) in reducing the rebleeding rate (pri