T1885 TRPV1 Induced CA2+-Dependent Production of Platelet Activating Factor (PAF) in Human Esophageal Epithelial Cells
โ Scribed by Ma, Jie; Harnett, Karen M.; Behar, Jose; Biancani, Piero; Cao, Weibiao
- Book ID
- 123062326
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 52 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0016-5085
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Background: Platelet-activating factor (PAF), a potent proinflammatory phospholipid mediator, has been implicated in inducing intestinal inflammation in diseases such as inflammatory bowel disease (IBD) and necrotizing enterocolitis (NEC). However, its mechanisms of inducing inflammatory responses a
Platelet-activating-factor (PAF) is a potent, biologically active lipid mediator produced by several tissues, including brain. Its role in the central nervous system (CNS) is still unknown, even if its involvement in brain damage and neurotoxicity has been postulated. Its production by neural cells