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T1334 Inflammation, Inducible Neuronal Nitric Oxide Synthase Expression and Loss of Neuronal Nitric Oxide Synthase in the Myenteric Plexus of Diabetes Prone BB Rats Are Independent of the Presence of Overt Diabetes

✍ Scribed by Kindt, Sebastien; Vanden Berghe, Pieter; Boesmans, Werend; Tack, Jan F.

Book ID: 123382748
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 99 KB
Volume: 134
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(08)62490-7

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## Abstract Acrylamide (ACR) is a known industrial neurotoxic chemical. Evidence suggests that ACR neurotoxic effect is related to brain neurotransmission disturbances. Since nitric oxide (NO) acts as a neurotransmission modulator and is produced by nitric oxide synthase (NOS), the neuronal NOS (nN