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t(1;19) and t(12;17) in childhood acute lymphoblastic leukemia of pre-B type

โœ Scribed by Francesca Ghione; Dorotea Gargano; Carlo Guazzelli; Alma Lippi


Book ID
119103952
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
205 KB
Volume
31
Category
Article
ISSN
0165-4608

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## Abstract The t(1;19)(q23;p13), which results in a fusion of __TCF3__ (previously __E2A__) at 19p13 with __PBX1__ at 1q23, is one of the most common translocations in acute lymphoblastic leukemia (ALL). It is seen either as a balanced t(1;19) or as an unbalanced der(19)t(1;19); occasional cases w