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T1168 Effects of ERK Inhibitor AZD6244 on the Growth of Multidrug-Resistance Human Gastric Carcinoma Cell Lines

โœ Scribed by He, Suyu; Wang, Chunhui; Tang, Chengwei

Book ID
122093178
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
73 KB
Volume
138
Category
Article
ISSN
0016-5085

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The effect of tyrosine kinase inhibitor, erbstatin, on cell growth and mRNA expression of growth-factor/receptor system was examined in 6 human gastric-carcinoma cell lines. Erbstatin inhibited both EGF-induced and serum-stimulated cell growth of all 6 cell lines (TMK-I, MKN-I, -7, -28, -45, -74) in