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T-type Ca2+ channels and α1E expression in spermatogenic cells, and their possible relevance to the sperm acrosome reaction

✍ Scribed by Arturo Liévano; Celia M. Santi; Carmen.J. Serrano; Claudia L. Treviño; Anthony R. Bellvé; Arturo Hernández-Cruz; Alberto Darszon

Book ID
115932464
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
529 KB
Volume
388
Category
Article
ISSN
0014-5793

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The direct electrophysiological characterization of sperm Ca 2ϩ channels has been precluded by their small size and flat shape. An alternative to study these channels is to use spermatogenic cells, the progenitors of sperm, which are larger and easier to patch-clamp. In mouse and rat, the only volta