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T-regulatory-1 (Tr1) cells that prevent CD4+ T cell colitis inhibit the antigen-presenting function and IL-12 production of dendritic cells

✍ Scribed by Yingzi Cong; Casey T. Weaver; Audrey Lazenby; Charles O. Elson


Book ID
119429053
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
189 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract The basis of the adjuvant effect of IL‐1 on the clonal expansion of Ag‐specific CD4 T cells was measured __in vivo__ using the TCR transgenic T cell adoptive transfer method. Injection ofAg plus IL‐1 caused naive CD4 T cells to proliferate to a greater extent than did injection of Ag al