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T Helper Cell-Independent Antibody Responses to the Transgene Product of an E1-Deleted Adenoviral Vaccine Require NK1.1 T Cells

✍ Scribed by Z.Q. Xiang; G.P. Gao; Y. Li; J.M. Wilson; H.CJ. Ertl


Book ID
112274289
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
140 KB
Volume
305
Category
Article
ISSN
0042-6822

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## Abstract ## Background The ability to induce cytotoxic T lymphocyte (CTL) responses that are multispecific is considered to comprise an essential feature for an efficacious genetic vaccine against many pathogens including HIV and hepatitis C virus. Ξ”E1Ad vectors are promising vectored vaccines