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T-Helper 17 Cells in Psoriatic Plaques and Additional Genetic Links between IL-23 and Psoriasis

✍ Scribed by Blauvelt, Andrew


Book ID
109875349
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
786 KB
Volume
128
Category
Article
ISSN
0022-202X

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## Background: We analyzed the influence of Crohn's disease (CD)associated IL23R gene variants on IL-22 that is expressed in IL-23Rϩ Th17 cells. Methods: IL-22 serum levels were measured in 242 CD patients and in 31 healthy controls. Subanalyses included serum levels of IL-6, TNF-␣, IL-17A, IL-17