## Abstract The aim of this work was to evaluate the involvement of survival pathways in the response of Jurkat T leukaemic cells sensitive to the cytotoxic action of tumour necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL)/Apo2L. Jurkat T cells express TRAIL‐R2/DR5 and TRAIL‐R4/DcR2
✦ LIBER ✦
T cell-to-T cell clustering enhances NF-κB activity by a PI3K signal mediated by Cbl-b and Rho
✍ Scribed by Thomas M. Herndon; Dana M. Pirone; George C. Tsokos; Christopher S. Chen
- Book ID
- 116290660
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 708 KB
- Volume
- 332
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Jurkat T leukemic cells respond to Etoposide, antineoplastic agent which targets the DNA unwinding enzyme, Topoisomerase II, and TNF‐Related‐Apoptosis‐Inducing‐Ligand (TRAIL), 34 kDa transmembrane protein, which displays minimal or no toxicity on normal cells and tissues, not only discl
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