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T-cell targeted therapies in autoimmune diseases

✍ Scribed by Fatima Alnaimat; Paramvir Sidhu; Sujata Sarkar

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
132 KB
Volume
72
Category
Article
ISSN
0272-4391

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The vertebrate immune system has evolved to protect against invasive pathogens, but with this adaptation comes the risk of autoimmunity, the recognition and destruction of self tissues by cells of the immune system. To avoid this problem the system has evolved active mechanisms by which tolerance is