T cell subsets in infectious and autoimmune diseases. D. Chadwick and G. Cardew (Eds). John Wiley & Sons: Chichester. ix + 262 pages, £ 50.00 (1995).

✍ Scribed by L. E. Glynn

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 208 KB
• Volume: 14
• Category: Article
• ISSN: 0263-6484
• DOI: 10.1002/cbf.676

✦ Synopsis

Book reviews

RAPID FREEZING, FREEZE FRACTURE, AND DEEP ETCHING N. J. Severs and D. M. Shotton (Eds). John Wiley, Chichester. xi + 372 pages, &95 (1995).

This book gives an up to date view of rapid freezing, freeze fracture and deep etching techniques in biological electron microscopy. Divided into 17 chapters written by experts in their field it provides a comprehensive volume of modern technique, applications, and interpretation of frozen biological tissues. Each chapter concludes with references and is thus a subject review in its own right. Chapter 1 is a 'potted history' outlining freeze fracture, deep etching and terminology. Chapters 2 and 3 describe techniques and equipment, and chapter 4 outlines potential artifacts. Each further chapter builds on previous sections to provide a comprehensive account, with later chapters dealing with the complementary use of the scanning electron microscope, the extracellular matrix, and viruses. The book contains numerous diagrams, tables, and high quality micrographs which clearly complement the text. It is a pity that safety is not often mentioned since cryogens are potentially dangerous and a small chapter on this subject would be appropriate.

In conclusion this book is well written and can be treated as a source reference or practical handbook which, although not for the beginner, gives a clear state of the art view of the subject.