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T-cell responses against products of oncogenes: Generation and characterization of human T-cell clones specific for p21 ras-derived synthetic peptides

✍ Scribed by Gedde-Dahl, Tobias; Eriksen, Jon Amund; Thorsby, Erik; Gaudernack, Gustav


Book ID
122705052
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
667 KB
Volume
33
Category
Article
ISSN
0198-8859

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Generation of cytotoxic-T-lymphocyte (CTL) responses against mutated ras peptides from peripheral-blood mononuclear cells (PBMC) was attempted in a group of HIA-A2.I+ healthy donors. Bulk PBMC cultures were stimulated in vitro with a mixture of peptides encompassing I 2 Gly + Val, 6 I Gln + Lys or 6