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T cell recognition of donor major histocompatibility complex class Ipeptides during allograft rejection

✍ Scribed by Josef Fangmann; Rosemarie Dalchau; Greta J. Sawyer; Carol A. Priestley; John W. Fabre

Book ID
102822816
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
646 KB
Volume
22
Category
Article
ISSN
0014-2980

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We have re-investigated the roles of CD4 and CD8 T cell subsets in skin graft rejection across a single class I MHC disparity. Recipient mice were transplanted with skin from donors transgenic for the class I MHC molecule K b . As expected, CD8 T cells were sufficient for rapid injection; but surpri