## Abstract We studied rearrangement of human T cell receptor genes (TCR) of Cβ, Cγ, Vγ and Jγ in 34 cases of adult T cell leukemia/lymphoma (ATLL), consisting of 29 cases with monoclonally integrated HTLV‐I proviral DNA (ATLL‐W) and five without monoclonal integration (ATLL‐O), in comparison with
✦ LIBER ✦
T cell receptor β-chain gene rearrangement without γ-chain gene rearrangement in cutaneous T cell lymphoma: An unusual finding
✍ Scribed by Vincent C. Ho; Erik R. Hansen; James T. Elder; Ole Baadsgaard; Gunhild L. Vejlsgaard; Curtis A. Hanson; Kevin D. Cooper
- Book ID
- 118375202
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 625 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1090-2341
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## Detection of clonal T-cell receptor (TCR )-chain gene rearrangement is a promising approach to distinguish between cutaneous T-cell lymphomas (CTCLs) and reactive T-cell infiltrates. Despite the improved sensitivity by using the polymerase chain reaction (PCR) rather than Southern blot analysis