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T cell receptor V gene usage by CD4+ and CD8+ peripheral blood T lymphocytes in immune thrombocytopenic purpura

✍ Scribed by I Hedlund-Treutiger; G Elinder; H Wigzell; J Grunewald; J Wahlström


Book ID
114814115
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
72 KB
Volume
93
Category
Article
ISSN
0803-5253

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The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of a and p variable region chains present in the T cell receptor complex. Currently, the Vp chains are grouped into 25 families. Historically, determination of Vp usage has relied on d