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T-Cell Receptor Use in Rheumatoid Arthritis

✍ Scribed by SHELDON M. COOPER; PETER E. LIPSKY

Book ID
119872379
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
285 KB
Volume
756
Category
Article
ISSN
0890-6564

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Clonally expanded CD4+CD28null T cells i
Clonally expanded CD4+CD28null T cells in rheumatoid arthritis use distinct combinations of T cell receptor BV and BJ elements
✍ Ulf Wagner; Matthias Pierer; Sylke Kaltenhäuser; Bernd Wilke; Wolfram Seidel; Sy 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB

Clonally expanded, autoreactive CD4(+)CD28(null) cells can be found in the peripheral blood of patients with rheumatoid arthritis and have been shown to be associated with severeextra-articular disease manifestations. We investigated the size of the CD4(+)CD28(null) compartment and the TCR beta chai