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T-cell receptor transgenic mice in the study of autoimmune diseases

โœ Scribed by Juan J Lafaille


Book ID
116613823
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
230 KB
Volume
22
Category
Article
ISSN
0896-8411

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## Inhibition of abnormal T cell development and autoimmunity in gld mice by transgenic T cell receptor p chain* Mice homozygous for the gld (generalized lymphoproliferative disease) mutation develop systemic autoimmune disease and severe lymphadenopathy due to an age-related accumulation in the p