T-cell receptor repertoire and function in umbilical cord blood lymphocytes from newborns of type 1 diabetic mothers
β Scribed by B. J. Manfras; S. Claudi-Boehm; R. Kreienberg; B. O. Boehm
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 201 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0940-5429
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The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of a and p variable region chains present in the T cell receptor complex. Currently, the Vp chains are grouped into 25 families. Historically, determination of Vp usage has relied on d
Islet cell antibodies are usually detected in the sera of almost all Type i (insulin-dependent) diabetic patients within several months after onset of the disease. The antibodies then disappear quite early during the course of the disease. The present study was undertaken to detect islet cell antibo