✦ LIBER ✦

T-cell receptor and T-cell-resistant virus variants

✍ Scribed by Yusuke Yanagi

Book ID: 103972739
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 677 KB
Volume: 3
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(91)90003-j

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✦ Synopsis

Analysis of the T-cell receptor has revealed the molecular basis of antigen recognition by T cells specific for viral antigens. Studies using T-cell receptor transgenic mice have provided evidence for clonal deletion of virus-specific T cells in persistently infected hosts and for selection of T-cell-resistant virus variants in vivo.

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