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T-Cell Prolymphocytic Leukemia With Hemorrhagic Gastrointestinal Involvement and a New Chromosomal Abnormality

✍ Scribed by Shigeo Toyota; Norihiko Nakamura; Kazuo Dan


Book ID
105675333
Publisher
Carden Jennings Publishing
Year
2002
Tongue
English
Weight
833 KB
Volume
75
Category
Article
ISSN
0925-5710

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## Abstract T‐cell prolymphocytic leukemia (T‐PLL) is a rare malignant proliferation of lymphoid cells with a postthymic phenotype. Previous cytogenetic and molecular studies reported complex karyotypes with recurrent chromosomal abnormalities, including translocations involving either __TCL1__ at

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We report a lS-month+ld boy with acute leukemic cells demonstrated a translocation myelornonocytic leukemia [French-Ameri-46,XY, t(9;11)(p24;q12) that has not been d e can-British classification M4 (FAB-M4)] whose scribed previously.

T-cell prolymphocytic leukemia with help
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The majority of published cases of prolymphocytic leukemia (PLL) have been of B-cell origin. Nineteen cases of PLL of T-cell type have been described, as has a single case of PLL having a surface phenotype with features of both B-cells and T-cells. This report presents a review of these cases and co