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T-Cell Large Granular Lymphocytic Leukemia and Pure Red Cell Aplasia in a Patient With Type I Autoimmune Polyendocrinopathy: Response to Immunosuppressive Therapy

✍ Scribed by DHODAPKAR, MADHAV V.; LUST, JOHN A.; PHYLIKY, ROBERT L.


Book ID
122499149
Publisher
Mayo Clinic
Year
1994
Tongue
English
Weight
422 KB
Volume
69
Category
Article
ISSN
0025-6196

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Pure red cell aplasia (PRCA) is an unusual complication of chronic lymphoproliferative disorders. A patient with T-cell chronic lymphocytic leukemia (T-CLL) had severe anemia and neutropenia. Initial in vitro studies demonstrated no evidence of T-cell suppression of erythropoiesis. Sequential bone m