T-cell dependence of immune response to hepatitis B antigen in mice
β Scribed by ROBERTS, ISABEL M.; BERNARD, CLAUDE C.; VYAS, GIRISH N.; MACKAY, IAN R.
- Book ID
- 109695084
- Publisher
- Nature Publishing Group
- Year
- 1975
- Tongue
- English
- Weight
- 256 KB
- Volume
- 254
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/254606a0
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Recent data suggest that genes involved in the control of (1) immune responses of humans to HBsAg and (2) the susceptibility to the development of chronic hepatitis B are linked to the major HLA histocompatibility complex. Studies on the genetic regulation of anti-HBs responses and on the possible a
The hepatitis B virus genome encodes a transcriptional transactivator protein designated HBxAg. We have investigated whether this antigen is a target structure for human T-lymphocytes. Using recombinant HBxAg protein, we found HBxAg-specific stimulation of peripheral blood mononuclear cells in patie