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T cell costimulatory blockade as a novel immune intervention in autoimmune diseases

โœ Scribed by Nader Najafian; Samia J Khoury; Mohamed H Sayegh

Book ID
117564519
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
399 KB
Volume
19
Category
Article
ISSN
0738-081X

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Frequent clonal expansion of peripheral
Frequent clonal expansion of peripheral T cells in patients with autoimmune diseases: A novel detecting system possibly applicable to laboratory examination
โœ Kayo Masuko-Hongo; Tomohiro Kato; Satoshi Suzuki; Taichi Sekine; Manae Kurokawa; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 81 KB ๐Ÿ‘ 1 views

To investigate T cell involvement in antigen-specific immune responses, it is important to detect accumulating T cells at a clonal level in vivo. However, thus far the clinical application of such analyses has been limited. Here we have established novel primers to anneal with T cell receptor (TCR)