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T-cell-antigen recognition and the immunological synapse

✍ Scribed by Huppa, Johannes B.; Davis, Mark M.


Book ID
109953953
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
508 KB
Volume
3
Category
Article
ISSN
1474-1741

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Immunological synapse and microclusters:
✍ Takashi Saito; Tadashi Yokosuka πŸ“‚ Article πŸ“… 2006 πŸ› Elsevier Science 🌐 English βš– 337 KB

An immunological synapse (IS) is formed at the interface between antigen-presenting cells and T cells, and is believed to be the structure responsible for antigen recognition and T-cell activation. However, recent imaging analyses reveal that T-cell receptor microclusters (MCs) formed prior to IS ar