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T-cell antigen discovery (T-CAD) assay: a novel technique for identifying T cell epitopes

โœ Scribed by Michael J. Turner; C.Siddiq Abdul-Alim; Richard A. Willis; Terrence L. Fisher; Edith M. Lord; John G. Frelinger

Book ID
114050828
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
248 KB
Volume
256
Category
Article
ISSN
0022-1759

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## Microsatellite instability (MSI) caused by defective DNA mismatch repair (MMR) is a hallmark of hereditary nonpolyposis colorectal cancers (HNPCC) but also occurs in about 15% of sporadic tumors. If instability affects microsatellites in coding regions, translational frameshifts lead to truncate