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T- and B-Cell Nonresponsiveness to Self-αB-Crystallin in SJL Mice Prevents the Induction of Experimental Allergic Encephalomyelitis

✍ Scribed by Marianne J.B. van Stipdonk; Astrid A. Willems; Richard Verbeek; Claire J.P. Boog; Johannes M. van Noort


Book ID
112240320
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
90 KB
Volume
204
Category
Article
ISSN
0008-8749

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Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a