T-47 Thrombocytopenia and neutropenia during peginterferon plus ribavirin combination therapy in cirrhotic patients with HCV infection
โ Scribed by A. Iacobellis; M.R. Valvano; N. Minerva; R. Cozzolongo; G.A. Niro; A. Andriulli
- Book ID
- 118648302
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 59 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1590-8658
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## Abstract As combination therapy with peginterferon (PEGโIFN) and ribavirin has a high morbidity, identifying individuals with hepatitis C virus (HCV) who will not respond to the treatment would be beneficial. The early responses of serum HCV RNA levels to standard interferon (IFN) and PEGโIFN we
## Abstract A study was carried out to determine whether early viral dynamics retain prediction of the outcome of peginterferon (PEGโIFN) and ribavirin combination therapy based on different genetic polymorphisms near the __IL28B__ gene, the strongest baseline predictor of response to this therapy.