Systems Genetics: Methods and Protocols

✍ Scribed by Klaus Schughart, Robert W. Williams (eds.)

• Publisher: Humana Press
• Year: 2017
• Tongue: English
• Leaves: 605
• Series: Methods in Molecular Biology 1488
• Edition: 1
• Category: Library

✦ Synopsis

This volume focuses on the use of system genetic methods and the use of murine models to study the role of gene variants and environmental factors on human health and disease—what is now often called personalized or precision health care. The protocols in this book will help readers analyze genetic causes of heritable variation across a wide range of systems and traits using rodent models. The chapters in this book are separated into three sections that cover: 1) resources for systems genetics; 2) tools for analysis and integration in systems genetics; and 3) systems genetics use cases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and tools, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.

Practical and thorough, Systems Genetics: Methods and Protocols is a valuable resource for anyone who is interested in this diverse field.

✦ Table of Contents

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Front Matter....Pages 3-29
Front Matter....Pages 31-44
Front Matter....Pages 45-45
Back Matter....Pages 47-73
....Pages 75-120

✦ Subjects

Human Genetics