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Systems genetics for drug target discovery

✍ Scribed by Nadia M. Penrod; Richard Cowper-Sal-lari; Jason H. Moore


Book ID
116919066
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
308 KB
Volume
32
Category
Article
ISSN
0165-6147

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The mouse has become the premier mammalian system for the identification of the genetic basis of both mono-and oligogenic disorders, as well as the understanding of complex diseases with gene-gene and gene-environment interactions. The similarity between human and mouse genetic disease is sometimes