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Systems bioenergetics of creatine kinase networks: physiological roles of creatine and phosphocreatine in regulation of cardiac cell function

✍ Scribed by R. Guzun; N. Timohhina; K. Tepp; M. Gonzalez-Granillo; I. Shevchuk; V. Chekulayev; A. V. Kuznetsov; T. Kaambre; V. A. Saks

Book ID
106222335
Publisher
Springer
Year
2011
Tongue
English
Weight
985 KB
Volume
40
Category
Article
ISSN
0939-4451

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Canine cardiac sarcoplasmic reticulum is phosphorylated by adenosine 3',5'-monophosphate (cAMP)-dependent and by calcium.calmodulin-dependent protein kinases on a 27,000 proteolipid, called phospholamban. Both types of phosphorylation are associated with an increase in the initial rates of Ca2+ tran