Approaches to avermectin assembly: Synth
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Anthony G.M. Barrett; Tony M. Raynham
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Article
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1987
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Elsevier Science
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French
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A chiral synthesis of the spiroketal moiety of avermectin A2b has been accomplished in 14 steps from (3S(R),&R(S))-3,5-dimethyl-1-hexen-4-01. The avermectins and the structurally related milbemycins have attracted considerable