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Systemic treatments with GM1 ganglioside reduce quinolinic acid-induced striatal lesions in the rat

✍ Scribed by Grazia Lombardi; Renzo Zanoni; Flavio Moroni


Book ID
115882902
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
196 KB
Volume
174
Category
Article
ISSN
0014-2999

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Striatal ganglioside levels in the rat f
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Ganglioside and DNA levels were estimated in the striatum of rats 10 days and 6 weeks after lesioning by intrastriatal injection of kainic acid. There was a moderate, 21-24% decrease of the ganglioside concentration per unit protein on the side of the lesion, which can be ascribed to the loss of the