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Systemic treatment with interleukin-4 induces regression of pulmonary metastases in a murine renal cell carcinoma model

โœ Scribed by Gilda G. Hillman; Elia Younes; Daniel Visscher; Esa Ali; John S. Lam; Emily Montecillo; J.Edson Pontes; Gabriel P. Haas; Raj K. Puri


Book ID
113135102
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
869 KB
Volume
160
Category
Article
ISSN
0008-8749

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## BACKGROUND. Interleukin-2 (IL-2) and granulocyte-macrophageฯชcolony stimulating factor (GM-CSF) are cytokines with nonoverlapping pleiotropic effects. In a prior Phase Ib study, this combination of agents exhibited antitumor effects in the lungs of four of eight patients with renal cell carcinoma