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Systemic therapy in the management of metastatic or locally recurrent adenoid cystic carcinoma of the salivary glands: a systematic review

✍ Scribed by Scott A Laurie; Alan L Ho; Matthew G Fury; Eric Sherman; David G Pfister

Book ID: 117785499
Publisher: The Lancet
Year: 2011
Tongue: English
Weight: 140 KB
Volume: 12
Category: Article
ISSN: 1470-2045
DOI: 10.1016/s1470-2045(10)70245-x

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## Abstract ## BACKGROUND: Bortezomib, an inhibitor of the 26S proteasome and NF‐κB, may have antitumor activity in adenoid cystic carcinoma (ACC). Preclinical studies have shown synergy between bortezomib and doxorubicin. ## METHODS: Eligibility criteria included incurable ACC, any number of pr