Postmortem examination o f t h e b r a i n s o f p a t i e n t s d y i n g w i t h SLE have, i n general, been l i m i t e d t o l i g h t microscopy. The two l a r g e s t s t u d i e s , a l t h o u g h separated by more t h a n t e n years, a r e remarkably s i m i l a r ( 1 , Z ) . They found t
Systemic Lupus Erythematosus Involving the Nervous System: Presentation, Pathogenesis, and Management
โ Scribed by Julia J. Rhiannon
- Book ID
- 107568351
- Publisher
- Humana Press Inc
- Year
- 2008
- Tongue
- English
- Weight
- 132 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1080-0549
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## Abstract The records of 37 patients with systemic lupus erythematosus (SLE) followed at The Children's Hospital of Philadelphia between 1968 and 1978 were reviewed for evidence of central nervous system (CNS) involvement. Criteria for CNS involvement included evidence of organic brain syndrome,
Management of central nervous system (CNS) involvement is one of the most challenging problems in systemic lupus erythematosus. This article reviews the spectrum of CNS manifestations present in this disease, their diagnosis and pathogenesis, as well as an approach to their treatment and prognostic