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Systemic absorption after local intracolonic vancomycin in pseudomembranous colitis

✍ Scribed by Miralem Pasic; Thierry Carrel; Milos Opravil; Tomislav Mihaljevic; Ludwig von Segesser; Marko Turina

Book ID
119067218
Publisher
The Lancet
Year
1993
Tongue
English
Weight
164 KB
Volume
342
Category
Article
ISSN
0140-6736

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The titled compound is a cyclodextrin derivative in which prednisolone 21-succinate (PDsuc) is covalently bound to one of the secondary hydroxyl groups of a-cyclodextrin (a-CyD) via an ester linkage. In this study, the PDsuc-appended a-CyD ester conjugate (PDsuc/a-CyD conjugate) was intracolonically